RT @FrontOncology: 📄 "Inactivation of the E3 ubiquitin ligase Fbw7 in cancer cells results in the stabilization of nuclear/active SREBP1z,…
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📄 "Inactivation of the E3 ubiquitin ligase Fbw7 in cancer cells results in the stabilization of nuclear/active SREBP1z, resulting in activation of lipid synthesis." 👨⚕️👩⚕️ Maria Bengoechea-Alonso et al Available #OpenAccess 👉 https://t.co/KDiVekspcP #
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Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of the PI3K-AKT signalling axis: The sterol regulatory-element binding proteins (SREBPs) are transcription factors controlling… #oncology https://t.co/Pf
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RT @FrontOncology: New research: Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of…