Title |
The Intestinal Microbiota and Viral Susceptibility
|
---|---|
Published in |
Frontiers in Microbiology, January 2011
|
DOI | 10.3389/fmicb.2011.00092 |
Pubmed ID | |
Authors |
Julie K. Pfeiffer, Justin L. Sonnenburg |
Abstract |
Many infections start with microbial invasion of mucosal surfaces, which are typically colonized by a community of resident microbes. A growing body of literature demonstrates that the resident microbiota plays a significant role in host susceptibility to pathogens. Recent work has largely focused on the considerable effect that the intestinal microbiota can have upon bacterial pathogenesis. These studies reveal many significant gaps in our knowledge about the mechanisms by which the resident community impacts pathogen invasion and the nature of the ensuing host immune response. It is likely that as viral pathogens become the focus of studies that examine microbiota-host interaction, substantial effects of resident communities exerted via diverse mechanisms will be elucidated. Here we provide a perspective of the exciting emerging field that examines how the intestinal microbiota influences host susceptibility to viruses. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Netherlands | 1 | <1% |
France | 1 | <1% |
Canada | 1 | <1% |
Unknown | 102 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 27% |
Researcher | 28 | 26% |
Student > Bachelor | 11 | 10% |
Professor > Associate Professor | 7 | 7% |
Other | 6 | 6% |
Other | 15 | 14% |
Unknown | 11 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 50 | 47% |
Immunology and Microbiology | 18 | 17% |
Biochemistry, Genetics and Molecular Biology | 16 | 15% |
Medicine and Dentistry | 6 | 6% |
Engineering | 2 | 2% |
Other | 4 | 4% |
Unknown | 11 | 10% |