@tiras_corner @washredacted Why do people with homozygous FH get coronary disease in their 20s? Why do people with very low LDL due to rare genetic variants have lower risk of coronary disease? https://t.co/XrkgXG8nZF
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@efb_1 People born with genetic variants that cause low cholesterol have fewer cardiac events.
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@StanziAck @holmanm So you think observations like this are coincidence? Or part of the conspiracy? https://t.co/0WioU9cAsf
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@JohnKastelein @ianriddockmd @sachinthemoment @JoshJwageman Looks like some low MW apoBs on LDLs are associated with hypobeta. Rare protein-truncating variants in apolipoprotein B gene is associated with lower LDLc See https://t.co/3fQjwhTd01 and https://