Mycobacterial protein PE_PGRS30 induces macrophage apoptosis through prohibitin 2 mitochondrial function interference

Overview of attention for article published in Frontiers in Microbiology, January 2023

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Mycobacterial protein PE_PGRS30 induces macrophage apoptosis through prohibitin 2 mitochondrial function interference https://t.co/1P1c60aZMX https://t.co/xmn83oDpx9

13 Feb 2023

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Mycobacterial protein PE_PGRS30 induces macrophage apoptosis through prohibitin 2 mitochondrial function interference https://t.co/amMqH5JQmc https://t.co/Z9wWjA5vfi

13 Feb 2023

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https://t.co/EkUAyHFGFI "The maintenance of mitochondrial structure by PHB2 was impaired in response to the PGRS domain. These results indicated that PE_PGRS30 reduces PHB2 in mitochondria, resulting in mitochondrial dysfunction and cellular apoptosis."

03 Feb 2023

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https://t.co/EkUAyHFGFI "PE_PGRS30 and PHB2 interact via the PGRS domain and mitochondrial targeting sequence, respectively. PHB2 overexpression reduced macrophage apoptosis in response to PE_PGRS30. PE_PGRS30 co-localized with PHB2, not in mitochondria,

03 Feb 2023

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