Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function

Open Access UCL Research: Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function https://t.co/KewlE92DIZ

I am excited to share that our research has been published in @FrontImmunol. We have demonstrated that a few amino acid changes in the TCR variable domains can enhance TCR expression, which results in a boosted antigen specific T cell function with more th

New Research: Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function: T cell receptor (TCR) gene modified T cells are a promising form of adoptive cellular therapy 30 against… https://t.co/qZv