We have previously shown that the key immune checkpoint protein PD-L1 is upregulated on DFT cells in response to interferon-gamma and developed monoclonal antibodies that can block PD-1 from interacting with PD-L1. @pseudokinase https://t.co/mksoGr1LA1
1,576 followers
1,576 followers
My first devil paper hit 5000 views this week! PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment https://t.co/19dSfMCeS7
32,780 followers
RT @WildImmunity: Would immune checkpoint immunotherapy work for the #Tasmanian #devil facial tumor disease #DFTD. DFT cells upregulate #PD…
1,576 followers
Would immune checkpoint immunotherapy work for the #Tasmanian #devil facial tumor disease #DFTD. DFT cells upregulate #PDL1 in response to IFN-gamma treatment. @FrontImmunol @ResearchMenzies @UTAS_MPH @UTAS_ https://t.co/mksoGr1LA1