RT @ConradEnge98050: #ALS and frontotemporal dementia exhibit #autoimmune inflammation from IL-17A (lymphoid, Th17 cells) before neurologic…
#ALS and frontotemporal dementia exhibit #autoimmune inflammation from IL-17A (lymphoid, Th17 cells) before neurological symptoms. More potential for $CRVS #ITK inhibitor #soquelitinib that can stop #Th17 cells and reduce IL-17A: https://t.co/W79HKCgIJu
@JamesEKrause Great read on T-cells and connection to neural inflammation and Alzheimer's. I actually commented on this and used article image to show that $CRVS upstream ITK inhibition stops Th17 cells and stops IL-17A and RORγ downstream. https://t.co/
@adpdnet Aβ42 soluble is necessary for brain function, but when inflammed by IL-17A they deposit into plaques and progress AD. $CRVS ITKi #soquelitinib stops #Th17 and IL-17A, should prevent deposits, radical new approach to AD! https://t.co/W79HKCgI