Chapter title |
Study of Transposable Elements and Their Genomic Impact
|
---|---|
Chapter number | 1 |
Book title |
Transposons and Retrotransposons
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3372-3_1 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3370-9, 978-1-4939-3372-3
|
Authors |
Muñoz-Lopez, Martin, Vilar-Astasio, Raquel, Tristan-Ramos, Pablo, Lopez-Ruiz, Cesar, Garcia-Pérez, Jose L, Martin Muñoz-Lopez Ph.D., Raquel Vilar-Astasio, Pablo Tristan-Ramos, Cesar Lopez-Ruiz, Jose L. Garcia-Pérez, Garcia-Pérez, Jose L., Martin Muñoz-Lopez |
Editors |
Jose L. Garcia-Pérez |
Abstract |
Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book. |
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