Henry C. Ideker, Ronald J. Walker, Angela Mazul, Sean T. Massa
Abstract
Survival of laryngeal cancer is decreasing; thus, optimal treatment selection is paramount. Specifically, T3 disease survival appears similar with surgical or non-surgical management; however, the implications of vocal cord fixation on treatment selection and survival are unknown. This study seeks to determine if surgical treatment of patients with T3M0 laryngeal cancer with vocal cord fixation is associated with superior survival compared to non-surgical treatment.
The National Cancer Database (NCDB) was queried for all T3M0 laryngeal carcinoma cases from 2004 to 2015, whose treatment included surgery or radiation therapy. Cases were stratified by cord fixation status and overall survival was compared using multivariable methods based on surgical versus non-surgical management.
Non-surgical management was more common, regardless of cord fixation status (84% in fixed and 79% in mobile). Cord fixation itself did not influence survival; however, surgical management had a significant survival benefit in the fixed cohort (HR = 0.843; 95% CI: 0.738, 0.962).
In this large observational cohort study of T3M0 laryngeal cancer, those with fixed cords had superior survival when managed surgically.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2023.
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#8,509,253
of 26,180,352 outputs
Outputs from Annals of Otology, Rhinology & Laryngology
#295
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Outputs of similar age
#127,726
of 369,421 outputs
Outputs of similar age from Annals of Otology, Rhinology & Laryngology
#5
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Altmetric has tracked 26,180,352 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,918 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 84% of its peers.
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
