small OL trial: anergic-anhedonic clinical presentations in TRD could benefit from pro-dopaminergic interventions. QIDS remission improved from 52% to 77%. There was a benefit in combining MAOI with pramipexole which was maintained for at least 18 months h
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Multiple attempts now to subtype depression based on Sx. Right path. “Among treatment-resistant depression (TRD), we identified anergic-anhedonic clinical presentations (TRAD) as putatively responsive to pro-dopaminergic strategies” https://t.co/90SaIRB
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New Research: Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial – CADOT: Introduction Among treatment-resistant depression… #Psychiatry htt