8,429/ Spain (est. current tobacco smoking age 15+ was 24.5% in 2020) S=smoking (not specified if current or ever; "history" appeared once) Of 211 with mild-to-moderate SARS-CoV-2 infection, S=33.2% 14 hospitalized or died: S=57.1% https://t.co/VxUZK6
#Remdesivir, once incorporated into RNA (top panel), is rapidly removed by SARS-CoV-2 exonuclease (middle panel); however, in presence of the exonuclease inhibitor #Pibrentasvir, the incorporated Remdesivir is largely protected from excision (lower panel).
New Research: A retrospective real-world study of early short-course remdesivir in non-hospitalized COVID-19 patients at high risk for progression: low rate of hospitalization or death, regardless of immunocompetence status #pharmacology https://t.co/zSGvN