Zinc deficiency impairs axonal regeneration and functional recovery after spinal cord injury by modulating macrophage polarization via NF-κB pathway

RT @renesugar: Zinc deficiency impairs axonal regeneration and functional recovery after spinal cord injury by modulating macrophage polari…

https://t.co/iQL7bhJlM2 "Furthermore, zinc supplementation after SCI attenuated these zinc-deficiency-induced series of responses and improved motor function."

https://t.co/iQL7bhJlM2 "The inflammatory response exacerbated by zinc deficiency led to worsening motor function by inducing more apoptosis of oligodendrocytes and demyelination and inhibiting axonal regeneration in the lesion site compared to the normal

https://t.co/iQL7bhJlM2 "In macrophages after SCI, zinc deficiency promoted nuclear translocation of NF-κB, polarization to pro-inflammatory like phenotype and expression of pro-inflammatory cytokines."