Exploring the Neuroprotective Effects of Lithium in Ischemic Stroke: A literature review

@doc4care @CiaraGlenville @UBuffalo Lithium has multiple effects including effects on platelets: https://t.co/uKlSMDYktZ

https://t.co/FW5QwCaJZH "Lithium treatment alleviates cognitive deficits associated with cerebral perfusion injury by upregulating BDNF expression and activates the BDNF/TrkB pathway in cortical neurons to prevent glutamate excitotoxicity."

https://t.co/FW5QwCaJZH "the mitogen-activated protein kinase (MAPK)/ extracellular signal-regulated kinase (ERK) signaling pathway, brain-derived neurotrophic factor (BDNF), mammalian target of rapamycin (mTOR), and glutamate receptors."

https://t.co/FW5QwCaJZH "Numerous preclinical studies have demonstrated that lithium can act in multiple molecular pathways, including glycogen synthase kinase 3(GSK-3), the Wnt signaling pathway,"