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@granny2cents @Lindley2 @DylanaKneeshaw @CFJC_Today Absolutely! I can share several sources. Thank you for being curious. I will include more links below: https://t.co/l0pjOSDxFi https://t.co/qlrOkamMdO
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⑶After ≥4 intravesical BCG instillations ↑‘IL-1β,IL-6,TNFα’ mRNA/prot; F.4,5 TI comprises epigenet/metabolic reprogramming of i- i- cells →↑pro-inflamm ‘ ’ when challenged w 2° irrelevant bact/v stimul Myeloid cells (DC,Mφ) can develop TI foll BCG💉 https
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⑶ After ≥4 intravesical BCG instillations ↑mRNA/prot expression of ‘IL-1β, IL-6, TNFα’; F.4,5 Trained immunity comprises epigenetic/metabolic reprogramming of innate immune cells →↑pro-inflamm ‘ ’ when challenged w a 2ndary irrelevant bact/v stimulus http
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@taipan168 @DrJohnOrchard These findings are reported over and over again. https://t.co/Ctk6W8WWlM https://t.co/um3R7eyGdi https://t.co/By53yC1eqG https://t.co/xr837gVN0b https://t.co/gxvqOeCHBk