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Syringa oblata Lindl. Aqueous Extract Is a Potential Biofilm Inhibitor in S. suis

Overview of attention for article published in Frontiers in Pharmacology, January 2017
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Title
Syringa oblata Lindl. Aqueous Extract Is a Potential Biofilm Inhibitor in S. suis
Published in
Frontiers in Pharmacology, January 2017
DOI 10.3389/fphar.2017.00026
Pubmed ID
Authors

Jingwen Bai, Yanbei Yang, Shuai Wang, Lingfei Gao, Jianqing Chen, Yongzhi Ren, Wenya Ding, Ishfaq Muhammad, Yanhua Li

Abstract

Streptococcus suis (S. suis) is a zoonotic pathogen that causes severe disease symptoms in pigs and humans. Syringa oblata Lindl. distributed in the middle latitudes of Eurasia and North America were proved as the most development potential of Chinese Medicine. In this study, biofilm formation by S. suis decreased after growth with 1/2 MIC, 1/4 MIC, or 1/8 MIC of Syringa oblata Lindl. aqueous extract and rutin. Scanning electron microscopy analysis revealed the potential effect of Syringa oblata Lindl. aqueous extract and rutin against biofilm formation by S. suis. Using iTRAQ technology, comparative proteomic analyses was performed at two conditions: 1/2 MIC of Syringa oblata Lindl. aqueous extract treated and non-treated cells. The results revealed the existence of 28 proteins of varying amounts. We found that the majority of the proteins were related to cell growth and metabolism. We also found that Syringa oblata Lindl. Aqueous extract affected the synthesis enzymes. In summary, Syringa oblata Lindl. aqueous extract might be used to inhibit the biofilm formation effectively by S. suis, and the active ingredients of the Syringa oblate Lindl. aqueous extract is rutin. The content of rutin is 9.9 ± 0.089 mg/g dry weight.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 15%
Unspecified 1 8%
Student > Doctoral Student 1 8%
Other 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 6 46%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 1 8%
Unspecified 1 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Agricultural and Biological Sciences 1 8%
Other 1 8%
Unknown 7 54%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2017.
All research outputs
#20,400,885
of 22,950,943 outputs
Outputs from Frontiers in Pharmacology
#10,140
of 16,228 outputs
Outputs of similar age
#355,860
of 420,054 outputs
Outputs of similar age from Frontiers in Pharmacology
#111
of 184 outputs
Altmetric has tracked 22,950,943 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,228 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,054 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 184 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.