Title |
Central Control of Feeding Behavior by the Secretin, PACAP, and Glucagon Family of Peptides
|
---|---|
Published in |
Frontiers in endocrinology, February 2017
|
DOI | 10.3389/fendo.2017.00018 |
Pubmed ID | |
Authors |
Revathi Sekar, Lei Wang, Billy Kwok Chong Chow |
Abstract |
Constituting a group of structurally related brain-gut peptides, secretin (SCT), pituitary adenylate cyclase-activating peptide (PACAP), and glucagon (GCG) family of peptide hormones exert their functions via interactions with the class B1 G protein-coupled receptors. In recent years, the roles of these peptides in neuroendocrine control of feeding behavior have been a specific area of research focus for development of potential therapeutic drug targets to combat obesity and metabolic disorders. As a result, some members in the family and their analogs have already been utilized as therapeutic agents in clinical application. This review aims to provide an overview of the current understanding on the important role of SCT, PACAP, and GCG family of peptides in central control of feeding behavior. |
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Unknown | 1 | 100% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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Unknown | 39 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 11 | 28% |
Student > Ph. D. Student | 11 | 28% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Professor > Associate Professor | 2 | 5% |
Other | 3 | 8% |
Unknown | 7 | 18% |
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Medicine and Dentistry | 7 | 18% |
Neuroscience | 5 | 13% |
Biochemistry, Genetics and Molecular Biology | 4 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Other | 3 | 8% |
Unknown | 9 | 23% |