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RT @ConradEnge98050: ITK sits at the nexus between stimulatory TCR signaling (via LCK) AND inhibitory PD-1 pathway (via SHP2). Targeting…
RT @ConradEnge98050: ITK sits at the nexus between stimulatory TCR signaling (via LCK) AND inhibitory PD-1 pathway (via SHP2). Targeting…
ITK sits at the nexus between stimulatory TCR signaling (via LCK) AND inhibitory PD-1 pathway (via SHP2). Targeting ITK inhibition w/ safe, oral $CRVS soquelitinib is of significant value, combination therapy should improve upon anti-PD1s monotherapy!