Spontaneously hypertensive rats exhibit increased liver flavin monooxygenase expression and elevated plasma TMAO levels compared to normotensive and Ang II-dependent hypertensive rats

#gerontology #ecology #geriatrics #ecotoxicology (FMO3 is increased by accumulation of persistent organic pollutants, such as PCBs, in the liver.) Increased levels of the TMAO-producing liver enzyme FMO3 are associated with spontaneous hypertension. ht

#hepatology #ecotoxicology #microbiome #etiology Spontaneous hypertension was associated with elevated FMO3 (liver enzyme increased by dioxins and involved in TMAO synthesis), and higher plasma TMAO/TMA ratio. https://t.co/MLq9lwqIwq