Title |
Subcutaneous and Sublingual Immunotherapy in Allergic Asthma in Children
|
---|---|
Published in |
Frontiers in Pediatrics, April 2017
|
DOI | 10.3389/fped.2017.00082 |
Pubmed ID | |
Authors |
Sophia Tsabouri, Antigoni Mavroudi, Gavriela Feketea, George V. Guibas |
Abstract |
This review presents up-to-date understanding of immunotherapy in the treatment of children with allergic asthma. The principal types of allergen immunotherapy (AIT) are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). Both of them are indicated for patients with allergic rhinitis and/or asthma, who have evidence of clinically relevant allergen-specific IgE, and significant symptoms despite reasonable avoidance measures and/or maximal medical therapy. Studies have shown a significant decrease in asthma symptom scores and in the use of rescue medication, and a preventive effect on asthma onset. Although the safety profile of SLIT appears to be better than SCIT, the results of some studies and meta-analyses suggest that the efficacy of SCIT is better and that SCIT has an earlier onset than SLIT in children with allergic asthma. Severe, not controlled asthma, and medical error were the most frequent causes of SCIT-induced adverse events. |
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Australia | 1 | 33% |
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Unknown | 1 | 33% |
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Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Members of the public | 1 | 33% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Readers by professional status | Count | As % |
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Researcher | 10 | 11% |
Student > Master | 10 | 11% |
Other | 9 | 10% |
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Unknown | 29 | 32% |
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Nursing and Health Professions | 3 | 3% |
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