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Lapatinib–induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors

Overview of attention for article published in Breast Cancer Research, November 2013
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1 X user

Citations

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73 Mendeley
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Title
Lapatinib–induced NF-kappaB activation sensitizes triple-negative breast cancer cells to proteasome inhibitors
Published in
Breast Cancer Research, November 2013
DOI 10.1186/bcr3575
Pubmed ID
Authors

Yun-Ju Chen, Ming-Hsin Yeh, Meng-Chieh Yu, Ya-Ling Wei, Wen-Shu Chen, Jhen-Yu Chen, Chih-Yu Shih, Chih-Yen Tu, Chia-Hung Chen, Te-Chun Hsia, Pei-Hsuan Chien, Shu-Hui Liu, Yung-Luen Yu, Wei-Chien Huang

Abstract

Triple-negative breast cancer (TNBC), a subtype of breast cancer with negative expressions of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (HER2), is frequently diagnosed in younger women and has poor prognosis for disease-free and overall survival. Due to the lack of known oncogenic drivers for TNBC proliferation, clinical benefit from currently available targeted therapies is limited, and new therapeutic strategies are urgently needed.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
Ecuador 1 1%
Unknown 71 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 16%
Student > Ph. D. Student 11 15%
Researcher 8 11%
Student > Master 5 7%
Student > Doctoral Student 4 5%
Other 10 14%
Unknown 23 32%
Readers by discipline Count As %
Medicine and Dentistry 15 21%
Biochemistry, Genetics and Molecular Biology 11 15%
Agricultural and Biological Sciences 9 12%
Pharmacology, Toxicology and Pharmaceutical Science 8 11%
Engineering 2 3%
Other 4 5%
Unknown 24 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2013.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Breast Cancer Research
#1,705
of 2,052 outputs
Outputs of similar age
#169,158
of 224,666 outputs
Outputs of similar age from Breast Cancer Research
#23
of 33 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,666 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.