Title |
Radiation-Induced Oral Mucositis
|
---|---|
Published in |
Frontiers in oncology, May 2017
|
DOI | 10.3389/fonc.2017.00089 |
Pubmed ID | |
Authors |
Osama Muhammad Maria, Nicoletta Eliopoulos, Thierry Muanza |
Abstract |
Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has marked adverse effects on patient quality of life and cancer therapy continuity. It is a challenge for radiation oncologists since it leads to cancer therapy interruption, poor local tumor control, and changes in dose fractionation. RIOM occurs in 100% of altered fractionation radiotherapy head and neck cancer patients. In the United Sates, its economic cost was estimated to reach 17,000.00 USD per patient with head and neck cancers. This review will discuss RIOM definition, epidemiology, impact and side effects, pathogenesis, scoring scales, diagnosis, differential diagnosis, prevention, and treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 488 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 63 | 13% |
Student > Master | 60 | 12% |
Student > Postgraduate | 38 | 8% |
Other | 31 | 6% |
Researcher | 29 | 6% |
Other | 87 | 18% |
Unknown | 180 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 161 | 33% |
Nursing and Health Professions | 36 | 7% |
Biochemistry, Genetics and Molecular Biology | 21 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 18 | 4% |
Agricultural and Biological Sciences | 12 | 2% |
Other | 48 | 10% |
Unknown | 192 | 39% |