Title |
Systemic Lupus Erythematosus and Thyroid Autoimmunity
|
---|---|
Published in |
Frontiers in endocrinology, June 2017
|
DOI | 10.3389/fendo.2017.00138 |
Pubmed ID | |
Authors |
Silvia Martina Ferrari, Giusy Elia, Camilla Virili, Marco Centanni, Alessandro Antonelli, Poupak Fallahi |
Abstract |
Most of the studies present in the literature show a high prevalence, and incidence, of new cases of hypothyroidism and autoimmune thyroiditis (AT) in systemic lupus erythematosus (SLE) patients, overall in female gender. A limited number of cases of Graves' disease have been also reported in SLE patients, in agreement with the higher prevalence of thyroid autoimmunity. It has been also demonstrated that a Th1 predominance is associated with AT in SLE patients. Furthermore, a higher prevalence of papillary thyroid cancer has been recently reported in SLE, in particular in the presence of thyroid autoimmunity. However, studies in larger number of SLE patients are needed to confirm findings about thyroid cancer. On the whole, data from literature strongly suggest that female SLE patients, with a high risk (a normal but at the higher limit thyroid-stimulating hormone value, positive antithyroid peroxidase antibodies, a hypoechoic pattern, and small thyroid), should undergo periodic thyroid function follow-up, and appropriate treatments when needed. A careful thyroid monitoring would be opportune during the follow-up of these patients. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 80 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 16% |
Student > Bachelor | 7 | 9% |
Other | 7 | 9% |
Researcher | 7 | 9% |
Student > Doctoral Student | 6 | 8% |
Other | 14 | 18% |
Unknown | 26 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 49% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Immunology and Microbiology | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Nursing and Health Professions | 1 | 1% |
Other | 1 | 1% |
Unknown | 29 | 36% |