Title |
From Genes to Health – Challenges and Opportunities
|
---|---|
Published in |
Frontiers in Pediatrics, January 2014
|
DOI | 10.3389/fped.2014.00012 |
Pubmed ID | |
Authors |
Muhammad Ramzan Manwar Hussain, Asifullah Khan, Hussein Sheikh Ali Mohamoud |
Abstract |
In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian and complex trait inheritance. Charting the genetic basis of complex diseases - including pediatric cancer, and interpreting huge amount of next-generation sequencing data are among the major technical challenges to be overcome in order to understand the molecular basis of various diseases and genetic disorders. In this review, we provide insights into some major challenges currently hindering a better understanding of Mendelian and complex trait inheritance, and thus impeding medical benefits to patients. |
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India | 1 | 33% |
Switzerland | 1 | 33% |
Germany | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 33% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 11 | 85% |
Demographic breakdown
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Researcher | 3 | 23% |
Other | 1 | 8% |
Professor | 1 | 8% |
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Other | 2 | 15% |
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Medicine and Dentistry | 1 | 8% |
Other | 1 | 8% |
Unknown | 2 | 15% |