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Mendeley readers
Title |
Nitro-fatty acids: novel anti-inflammatory lipid mediators
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Published in |
Brazilian Journal of Medical and Biological Research, September 2013
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DOI | 10.1590/1414-431x20133202 |
Pubmed ID | |
Authors |
H. Rubbo |
Abstract |
Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue, modulating metabolic as well as inflammatory signaling pathways. Here we discuss the mechanisms of nitro-fatty acid formation as well as their key chemical and biochemical properties. The electrophilic properties of nitro-fatty acids to activate anti-inflammatory signaling pathways are discussed in detail. A critical issue is the influence of nitroarachidonic acid on prostaglandin endoperoxide H synthases, redirecting arachidonic acid metabolism and signaling. We also analyze in vivo data supporting nitro-fatty acids as promising pharmacological tools to prevent inflammatory diseases. |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Uruguay | 1 | 2% |
Unknown | 65 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 15% |
Student > Master | 10 | 15% |
Student > Ph. D. Student | 9 | 14% |
Student > Bachelor | 5 | 8% |
Student > Postgraduate | 4 | 6% |
Other | 13 | 20% |
Unknown | 15 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 17 | 26% |
Agricultural and Biological Sciences | 10 | 15% |
Chemistry | 8 | 12% |
Nursing and Health Professions | 4 | 6% |
Immunology and Microbiology | 2 | 3% |
Other | 7 | 11% |
Unknown | 18 | 27% |