Title |
Hodgkin’s-like lymphoma in a ferret (Mustela putorius furo)
|
---|---|
Published in |
Journal of Veterinary Medical Science, August 2017
|
DOI | 10.1292/jvms.17-0317 |
Pubmed ID | |
Authors |
Isao MATSUMOTO, Kazuyuki UCHIDA, James Kenn CHAMBERS, NIBE Kazumi, SATO Yu, Taku HAMASU, Hiroyuki NAKAYAMA |
Abstract |
A 7-year-old castrated male ferret developed unilateral cervical lymphadenomegaly over a 1-month period. Histological examination revealed proliferation of tumor cells in a diffuse and partially nodular pattern. The tumor cells were predominantly Hodgkin cells and binucleated Reed-Sternberg cells, characterized by abundant, clear, vacuolated cytoplasm, pleomorphic, ovoid nuclei with thick nuclear membranes and distinct nucleoli. Multinucleated cells, resembling lymphocytic and histiocytic (L&H) cells, were also observed. Immunohistochemically, the tumor cells expressed Pax-5, BLA-36 and vimentin. A small population of the tumor cells expressed CD20. This case showed proliferation of Hodgkin/Reed-Sternberg cells in conjunction with L&H cells that were histologically analogous to feline Hodgkin's-like lymphoma. However, Pax-5 and BLA-36 expression along with rare CD20 expression were consistent with classical Hodgkin's lymphoma in humans. |
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United Kingdom | 1 | 33% |
United States | 1 | 33% |
Unknown | 1 | 33% |
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Other | 2 | 20% |
Student > Master | 2 | 20% |
Lecturer | 1 | 10% |
Student > Doctoral Student | 1 | 10% |
Researcher | 1 | 10% |
Other | 0 | 0% |
Unknown | 3 | 30% |
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Veterinary Science and Veterinary Medicine | 6 | 60% |
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Unknown | 3 | 30% |