Title |
The Atg8 Family of Proteins—Modulating Shape and Functionality of Autophagic Membranes
|
---|---|
Published in |
Frontiers in Genetics, August 2017
|
DOI | 10.3389/fgene.2017.00109 |
Pubmed ID | |
Authors |
Iman Abdollahzadeh, Melanie Schwarten, Thomas Gensch, Dieter Willbold, Oliver H. Weiergräber |
Abstract |
Aging is a multifactorial process involving an accumulation of alterations on various organizational levels, which finally compromises viability and limits the lifespan of organisms. It is now well-established that many aspects of aging can be positively affected by (macro)autophagy, a mechanism of self-digestion found in virtually all eukaryotic cells. A comprehensive understanding of autophagy is thus expected to not only deepen our insight into the mechanisms of aging but to also open up new avenues toward increasing the healthy lifespan in humans. In this review, we focus on the Atg8 family of ubiquitin-like proteins, which play a crucial role in the autophagy process by virtue of their unique mode of reversible membrane association. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 18% |
Student > Ph. D. Student | 8 | 16% |
Student > Bachelor | 8 | 16% |
Researcher | 5 | 10% |
Student > Postgraduate | 4 | 8% |
Other | 6 | 12% |
Unknown | 10 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 17 | 34% |
Agricultural and Biological Sciences | 11 | 22% |
Medicine and Dentistry | 3 | 6% |
Neuroscience | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Other | 1 | 2% |
Unknown | 14 | 28% |