Title |
Fungal Polysaccharides: Biological Activity Beyond the Usual Structural Properties
|
---|---|
Published in |
Frontiers in Microbiology, January 2011
|
DOI | 10.3389/fmicb.2011.00171 |
Pubmed ID | |
Authors |
Marcio L. Rodrigues, Leonardo Nimrichter, Radames J. B. Cordero, Arturo Casadevall |
Abstract |
Studies on structure and function of polysaccharides in biological systems classically involve sequence and compositional analyses, anomeric configuration, type of glycosidic linkage, and presence of substituents. Recent studies, however, indicates that other structural parameters, so far little explored, can directly influence the biological activity of microbial polysaccharides. Among these parameters, we highlight the molecular dimensions of Cryptococcus neoformans polysaccharides, which appear to be inversely correlated with their immunobiological activity. These recent observations raise new concepts about the structure and function of polysaccharides, which stimulates the design of new experimental approaches and suggests previously unknown applications. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Slovenia | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 50 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 11 | 21% |
Researcher | 8 | 15% |
Student > Bachelor | 5 | 10% |
Student > Master | 5 | 10% |
Other | 4 | 8% |
Other | 11 | 21% |
Unknown | 8 | 15% |
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Arts and Humanities | 1 | 2% |
Other | 7 | 13% |
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