Title |
An evolutionary perspective on the Crabtree effect
|
---|---|
Published in |
Frontiers in Molecular Biosciences, October 2014
|
DOI | 10.3389/fmolb.2014.00017 |
Pubmed ID | |
Authors |
Thomas Pfeiffer, Annabel Morley |
Abstract |
The capability to ferment sugars into ethanol is a key metabolic trait of yeasts. Crabtree-positive yeasts use fermentation even in the presence of oxygen, where they could, in principle, rely on the respiration pathway. This is surprising because fermentation has a much lower ATP yield than respiration (2 ATP vs. approximately 18 ATP per glucose). While genetic events in the evolution of the Crabtree effect have been identified, the selective advantages provided by this trait remain controversial. In this review we analyse explanations for the emergence of the Crabtree effect from an evolutionary and game-theoretical perspective. We argue that an increased rate of ATP production is likely the most important factor behind the emergence of the Crabtree effect. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 3 | 75% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Chile | 1 | <1% |
Norway | 1 | <1% |
Netherlands | 1 | <1% |
Australia | 1 | <1% |
Ghana | 1 | <1% |
Spain | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 857 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 190 | 22% |
Student > Ph. D. Student | 144 | 17% |
Student > Master | 133 | 15% |
Researcher | 62 | 7% |
Student > Doctoral Student | 26 | 3% |
Other | 62 | 7% |
Unknown | 249 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 251 | 29% |
Agricultural and Biological Sciences | 159 | 18% |
Engineering | 39 | 5% |
Chemical Engineering | 36 | 4% |
Chemistry | 29 | 3% |
Other | 78 | 9% |
Unknown | 274 | 32% |