Title |
A Rare Case of Hepatic T-Cell Rich B-Cell Lymphoma (TCRBCL) in a Juvenile Dog
|
---|---|
Published in |
Journal of Veterinary Medical Science, October 2014
|
DOI | 10.1292/jvms.14-0088 |
Pubmed ID | |
Authors |
Tae-Ho CHUNG, Catherine LAMM, Young-Chul CHOI, Jung-Woo LEE, Dohyeon YU, Ul-Soo CHOI |
Abstract |
A 7-month-old castrated male French Bull dog was presented with vomiting, lethargy, anorexia and weight loss of 2 weeks duration. The patient's history and clinical manifestations of suspected hepatopathy were subjected to ultrasonography, radiography, biochemical investigations and cytology of hepatic lesion. The cytologic impression was hepatic lymphoma, which was later confirmed by histopathology. The neoplastic cells were strongly diffusely immunoreactive for PAX5, but not immunoreactive for CD3, and B lymphocyte specific clonal proliferation was detected using by assay of antigen receptor rearrangement. Large numbers of immunoreactive mature non-neoplastic lymphocytes were admixed with the neoplastic cell population. Therefore, the immunohistochemical results were definitively consistent with a T-cell rich B-cell lymphoma (TCRBCL). This is the first description of a hepatic TCRBCL in a juvenile dog showing a poor response to aggressive chemotherapy. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 3 | 17% |
Student > Ph. D. Student | 2 | 11% |
Student > Postgraduate | 2 | 11% |
Student > Master | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 2 | 11% |
Unknown | 7 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 28% |
Veterinary Science and Veterinary Medicine | 4 | 22% |
Agricultural and Biological Sciences | 1 | 6% |
Unknown | 8 | 44% |