Title |
Diagnosis and Treatment of Mucormycosis in Patients withHematological Malignancies[Translated Article]
|
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Published in |
Medical Mycology Journal, January 2017
|
DOI | 10.3314/mmj.17.013 |
Pubmed ID | |
Authors |
Yuki Asano-Mori |
Abstract |
The risk of invasive fungal infections (IFIs) is extremely high in patients with hematological malignancies due to the prolonged and profound neutropenia and immunosuppression after chemotherapy and hematopoietic stem cell transplantation. There has been increasing interest in mucormycosis despite its relatively uncommon occurrence, because occasional breakthrough infections have been observed under anti-Aspergillus prophylaxis. The aggressive nature of mucormycosis easily leads to high mortality because of delays in diagnosis and incorrect treatment decisions, which are due in part to lack of adjunctive diagnostic tools and having similar clinical and radiological features with invasive aspergillosis. The only currently available antifungals against Mucorales in Japan are amphotericin B formulations. Thus, comprehensive therapeutic strategies, including surgery, should be considered to achieve a successful outcome. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 4 | 15% |
Other | 3 | 11% |
Student > Bachelor | 3 | 11% |
Student > Ph. D. Student | 2 | 7% |
Student > Postgraduate | 2 | 7% |
Other | 2 | 7% |
Unknown | 11 | 41% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 30% |
Arts and Humanities | 1 | 4% |
Chemical Engineering | 1 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 3 | 11% |
Unknown | 12 | 44% |