Chapter title |
Eukaryotic Membranes and Cytoskeleton
|
---|---|
Chapter number | 5 |
Book title |
Eukaryotic Membranes and Cytoskeleton
|
Published in |
Advances in experimental medicine and biology, January 2007
|
DOI | 10.1007/978-0-387-74021-8_5 |
Pubmed ID | |
Book ISBNs |
978-0-387-74020-1, 978-0-387-74021-8
|
Authors |
Mironov, Alexander A, Banin, Victor V, Sesorova, Irina S, Dolgikh, Viacheslav V, Luini, Alberto, Beznoussenko, Galina V, Alexander A. Mironov, Victor V. Banin, Irina S. Sesorova, Viacheslav V. Dolgikh, Alberto Luini, Galina V. Beznoussenko, Mironov, Alexander A., Banin, Victor V., Sesorova, Irina S., Dolgikh, Viacheslav V., Beznoussenko, Galina V. |
Abstract |
By analyzing the morpho-physiological features of the Golgi complex, its relationship with the endoplasmic reticulum in different species, and the molecular machineries involved in intracellular transport, we conclude that; (1) all eukaryotic cells have either Golgi complexes or remnants thereof; (2) all eukaryotic cells have a large minimal set of proteins that are involved in intracellular transport; and (3) several indispensable molecular machines are always present in secreting eukaryotic cells. Using this information, our data about mechanisms of intra-Golgi transport and phylogenetic analysis of several molecular machines, we propose a model for the evolution of the Golgi complex and the endoplasmic reticulum. |
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