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Oral zinc augmentation with vitamins A and D increases plasma zinc concentration: Implications for burden of disease

Overview of attention for article published in Metabolic Brain Disease, August 2006
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  • Good Attention Score compared to outputs of the same age (71st percentile)

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10 X users
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1 Facebook page

Citations

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18 Dimensions

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37 Mendeley
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1 CiteULike
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Title
Oral zinc augmentation with vitamins A and D increases plasma zinc concentration: Implications for burden of disease
Published in
Metabolic Brain Disease, August 2006
DOI 10.1007/s11011-006-9023-4
Pubmed ID
Authors

F. C. V. Potocnik, S. J. van Rensburg, D. Hon, R. A. Emsley, I. M. Moodie, R. T. Erasmus

Abstract

A study evaluating zinc supplementation in patients with Alzheimer's disease yielded variable zinc plasma levels in spite of positive cognitive and physiological results. In an attempt to raise and sustain plasma zinc levels, a single patient was given 15 mg zinc/day with various combinations of vitamins. A sustained raise in plasma zinc concentration (and therefore its potential bioavailability) was obtained only when the zinc was augmented with both vitamins A and D (in RDA concentrations). In order to verify these results, a follow-up study was conducted in 70 volunteers. Seven groups of 10 healthy subjects received various combinations of zinc and the two vitamins A and D, namely: zinc, vitamin A, vitamin D, zinc plus vitamin A, zinc plus vitamin D, vitamins A and D, and zinc plus vitamins A and D. Plasma zinc levels were determined at baseline, 3 weeks and 6 weeks. Plasma zinc levels increased significantly (p < 0.02) from 11.82 (+/-2.60) to 13.32 (+/-3.04) mum/L only in the group receiving the combination of zinc and vitamins A and D. This novel method of increasing plasma zinc levels by the augmentation of vitamins A and D may have implications for the reduction of burden of disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Brazil 1 3%
Unknown 35 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 11%
Researcher 3 8%
Other 2 5%
Lecturer 2 5%
Professor 2 5%
Other 7 19%
Unknown 17 46%
Readers by discipline Count As %
Medicine and Dentistry 10 27%
Chemical Engineering 2 5%
Nursing and Health Professions 2 5%
Psychology 2 5%
Linguistics 1 3%
Other 1 3%
Unknown 19 51%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2021.
All research outputs
#6,500,512
of 25,967,806 outputs
Outputs from Metabolic Brain Disease
#320
of 1,183 outputs
Outputs of similar age
#25,489
of 90,527 outputs
Outputs of similar age from Metabolic Brain Disease
#1
of 3 outputs
Altmetric has tracked 25,967,806 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,183 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,527 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them