Title |
Concentration of Malondialdehyde in Subjects Living at High Altitudes: Exploratory Study.
|
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Published in |
Revista Peruana de Medicina Experimental y Salud Pública, January 2017
|
DOI | 10.17843/rpmesp.2017.344.2830 |
Pubmed ID | |
Authors |
Ingrid Gaby Melgarejo Pomar, Elfride Balanza Erquicia, Lizeth Torrez Colmena, Sergio Quisberth Barrera, Pilar Leina Suzaño Vargas |
Abstract |
The objective of this study was to determine the levels of malondialdehyde (MDA), an oxidative stress biomarker, in individuals living at high altitudes (3500-4200 m). This exploratory study evaluated 91 subjects from La Paz and El Alto using a questionnaire and clinical examination. MDA levels were measured using a colorimetric technique. Measures of central tendency, dispersion, and percentages were used to describe data, and the Mann-Whitney test and Kruskal-Wallis test were used to assess differences between the sexes, age groups, and altitudes. The median concentration of MDA was 4.1 μmol/L (RIC 2.4-5.4) and the highest concentration of MDA was found in individuals older than 40 years. The average MDA levels were higher than those found at sea level, a result we believe is due to the effect of hypoxia. However, there were no differences in the MDA levels between the sexes or age groups. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 20% |
Student > Doctoral Student | 2 | 10% |
Unspecified | 1 | 5% |
Student > Master | 1 | 5% |
Professor > Associate Professor | 1 | 5% |
Other | 1 | 5% |
Unknown | 10 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
Chemistry | 2 | 10% |
Unspecified | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Agricultural and Biological Sciences | 1 | 5% |
Other | 3 | 15% |
Unknown | 10 | 50% |