Shuxu Du, Yaqian Huang, Hongfang Jin, Tianyou Wang
Abstract
Over the past few decades, the number of long term survivors of childhood cancers has been increased exponentially. However, among these survivors, treatment-related toxicity, especially cardiotoxicity, is becoming the essential cause of morbidity and mortality. Thus, preventing the treatment-related adverse effects is important to increase the event free survival during the treatment of cancer in children and adolescents. Accumulating evidence has demonstrated that hydrogen sulfide (H2S) exerts a protective role on cardiomyocytes through a variety of mechanisms. Here, we mainly reviewed the cardioprotective role of H2S in the chemotherapy, and emphatically discussed the possible mechanisms.
Pharmacology, Toxicology and Pharmaceutical Science
3
13%
Biochemistry, Genetics and Molecular Biology
3
13%
Agricultural and Biological Sciences
3
13%
Chemistry
2
9%
Nursing and Health Professions
1
4%
Other
5
22%
Unknown
6
26%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2018.
All research outputs
#14,965,143
of 23,018,998 outputs
Outputs from Frontiers in Pharmacology
#5,296
of 16,331 outputs
Outputs of similar age
#255,664
of 440,577 outputs
Outputs of similar age from Frontiers in Pharmacology
#104
of 297 outputs
Altmetric has tracked 23,018,998 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,331 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,577 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 297 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
