Table of Contents

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   Book Overview
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   Chapter 1 Monochromatic X-Rays, Slow Neutrons, and Radionuclides for Targeted Radiotherapy
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   Chapter 2 Current Trends and Progress in the Physics of BNCT
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   Chapter 3 Chemistry and Pharmacology of Agents for BNCT
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   Chapter 4 The Harvard-MIT BNCT Program
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   Chapter 5 Boron Neutron Capture Therapy for Glioblastoma Multiforme
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   Chapter 6 Boron Neutron Capture Therapy
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   Chapter 7 Status Report on the European Clinical Trial of BNCT at Petten (EORTC Protocol 11961)
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   Chapter 8 Case Studies of Patients with Glioblastoma Multiforme Treated with Boron Neutron Capture Therapy at the Brookhaven Medical Research Reactor
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    Chapter 9 Patterns of Tumor Progression Following BNCT of Glioblastoma Multiforme
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    Chapter 10 Intercomparison of Three Epithermal Neutron-Based Clinical Trials of BNCT
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    Chapter 11 Report on the First Patient Group of the European Phase I Trial (EORTC Protocol 11961) at the High Flux Reactor Petten
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    Chapter 12 Quality Management at the European BNCT Center in Petten
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    Chapter 13 Psychological Aspects of the Patient Treatment by BNCT at Petten
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    Chapter 14 At the Threshold of Clinical Trials
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    Chapter 15 An Autopsy Report of a Glioblastoma Case after Boron Neutron Capture Therapy
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    Chapter 16 Long Term Follow up in Patients Who Underwent Boron Neutron Capture Therapy
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    Chapter 17 A Case of Astrocytoma
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    Chapter 18 Treatment Planning for the First Group of Patients in the European Glioma Trial at the HFR Petten
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    Chapter 19 Quality Assurance for Clinical Dosimetry of the European Trial on BNCT in Petten
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    Chapter 20 Medical Image Transfer and Conversion for BNCT Treatment Planning at Petten
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    Chapter 21 Patient Positioning at the HFR Petten
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    Chapter 22 Treatment Planning Based on Dynamic Positron Emission Tomography for Boron Neutron Capture Therapy for Glioblastoma Multiforme
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    Chapter 23 Acceleration of MCNP-Based Treatment Planning and the Application for In Vivo Boron Determination by the Gamma-Ray Telescope
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    Chapter 24 Integrated Medical Image Registration, Patient Positioning, and Patient Monitoring for Cranial BNCT
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    Chapter 25 Treatment Plan Evaluation in Boron Neutron Capture Therapy
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    Chapter 26 A Comparison of Two BNCT Treatment Planning Programs
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    Chapter 27 Three Dose Calculation Codes Applied to Neutron Transport in BNCT
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    Chapter 28 Source Characterization for the rtt_MC Treatment Planning Program at FiR 1
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    Chapter 29 “CARONTE”, A Treatment Planning System Based on Real Macroscopic Boron Distribution and MCNP-4A Code
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    Chapter 30 CASE-MATE: Computer-Aided Cell Seeding, Microcloning, Analysis, and Telemetric Evaluation Applied to Neutron Capture Therapy
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    Chapter 31 Standard Operating Procedures Followed by the Petten BNC-Team during Patient Treatment
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    Chapter 32 Predicting Boron-10 Concentrations in Normal Brain and GBM from Blood Measurements
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    Chapter 33 A Pharmacokinetic Model for the Concentration of Boron-10 in Blood Following Boronophenylalanine-Fructose Administration in Humans
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    Chapter 34 Quality Control for Na 2 B 12 H 11 SH, a Drug for Boron Neutron Capture Therapy in EORTC Trial 11961
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    Chapter 35 The Pharmacokinetics of BSH Following Single and Multiple Administrations
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    Chapter 36 Metamorphosis of a 35 Year-Old TRIGA Reactor into a Modern BNCT Facility
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    Chapter 37 Status of the Medical Irradiation Facility at JRR-4
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    Chapter 38 Clinical Protocol Using New Neutron Irradiation Facility (JRR4) at JAERI
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    Chapter 39 Upgrade of the Epithermal Neutron Beam Using 235 U Fission Plates at Brookhaven Medical Research Reactor (BMRR)
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    Chapter 40 TRIGA ® Fuel Based Converter Assembly Design for a Dual-Mode Neutron Beam System at the McClellan Nuclear Radiation Center
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    Chapter 41 BNCT Filter Design Studies at the CEA-Saclay ISIS Research Reactor
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    Chapter 42 Preparation of a Beam Tube of the Portuguese Research Reactor to be Used in BNC and Other Activites
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    Chapter 43 NCT Facility Development and Beam Characterisation at the RA-6 Reactor
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    Chapter 44 A NCT Facility Design at HANARO
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    Chapter 45 Beam Collimator Design for the Epithermal Neutron Beam at the Tsing Hua Open-Pool Reactor (THOR)
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    Chapter 46 The Usage of the KUR Advanced Clinical Irradiation System for NCT under the KUR Continous Operation
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    Chapter 47 Feasibility of the Utilization of BNCT in Thermalizing Column of TRIGA Reactor
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    Chapter 48 The Characteristics of the Updated Heavy Water Facility of the Kyoto University Reactor (II) (Neutron Energy Spectra for Several Irradiation Modes)
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    Chapter 49 The Test-Type Hyper-Thermal Neutron Generator for Neutron Capture Therapy
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    Chapter 50 What are the Best Energies for Neutron Production for NCT?
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    Chapter 51 The Use of Polytetrafluoroethylene (Teflon®) Containing Filter/ Moderators for Epithermal Neutron Beam Production
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    Chapter 52 Three-Dimensional Measurement of Thermal Neutron Absorbed Dose for BNCT Experimental Program, Performed in a Fast Research Reactor
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    Chapter 53 Validation of the Specification of the Epithermal Neutron Beam for Boron Neutron Capture at the HFR Petten
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    Chapter 54 Determination of the Geometric and Spectral Characteristics of BNCT Beam (Neutron and Gamma-Ray)
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    Chapter 55 BNCT Beam Quality Maximization
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    Chapter 56 A Biological Comparison of Neutron Beams Used for BNCT Research
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    Chapter 57 A Comparison of Neutron Fields for BNCT
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    Chapter 58 The BNCT Project in the Czech Republic before the Start of Clinical Treatment
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    Chapter 59 The Russian Project on Neutron Capture Therapy for Cancer
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    Chapter 60 Development of an Accelerator-Based BNCT Facility at the Berkeley Lab
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    Chapter 61 The Relationship Between BNCT Neutron Beam Parameters and Treatment Planning Figures-Of-Merit
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    Chapter 62 Development of a High-Power Water-Cooled Beryllium Target for use in Accelerator-Based Boron Neutron Capture Therapy
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    Chapter 63 A Sealed-Accelerator-Tube Neutron Generator for Boron Neutron Capture Therapy Application
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    Chapter 64 Construction of an Accelerator-Based Neutron Beamline for Treatment of Arthritic Joints
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    Chapter 65 Use of the 9 Be(d,n) Nuclear Reaction for Accelerator-Based Boron Neutron Capture Therapy
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    Chapter 66 An Experimental Program for BNCT Using a Thermal Accelerator-Based Source and the Epithermal Facility at the Tapiro Reactor
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    Chapter 67 Investigation of 2 H(d,n) 3 He and 3 H(d,n) 4 He Fusion Reactions as Alternative Neutron Sources for BNCT
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    Chapter 68 Spectral Characterization of Accelerator-Based Beams for BNCT Using Neutron Activation Foils
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    Chapter 69 Preliminary Study on Accelerator-Based Neutron Fields for NCT
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    Chapter 70 Experimental In-Phantom Dosimetry of the 7 Li(p,n) Reaction near Threshold
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    Chapter 71 Feasibility of a Near-Threshold BNCT Neutron Source Based on Phantom Dosimetry
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    Chapter 72 Analysis of Accelerator Based Neutron Spectra for BNCT Using Proton Recoil Spectroscopy
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    Chapter 73 Energy Optimization of Epithermal Neutron Beams for Accelerator-Based BNCT
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    Chapter 74 Applications of Californium-252 and the Californium User Facility for Neutron Capture Therapy Research
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    Chapter 75 Neutronic Design of a 252 Cf- 235 U Epithermal Irradiation Facility Applied to BNCT
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    Chapter 76 Measurement of Fast Neutron, Gamma, and Thermal Neutron Dose Around a Cf-252 Source
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    Chapter 77 Calculated Boron Neutron Capture Dose Enhancement in ICRU 44 Brain with 252 Cf
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    Chapter 78 Semiconductor Dosimetry in BNCT
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    Chapter 79 Reporting a BNCT Irradiation
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    Chapter 80 Radiation Risks from p -Boronophenylalanine-Mediated BNCT for Glioblastoma Multiforme
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    Chapter 81 Nominal Effective Radiation Doses Delivered to the Tumor and Different Parts of the Normal Brain During BNCT for Glioblastoma Multiforme
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    Chapter 82 Microdosimetry Studies at the BMRR and the MITR-II Using Miniature Tissue-Equivalent Proportional Counters
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    Chapter 83 Radiation Dosimetry for NCT Facilities at the Brookhaven Medical Research Reactor
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    Chapter 84 In Vivo Determination of Boron in Patients During BNCT in Petten by Means of the Gamma-Ray Telescope
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    Chapter 85 MCNP Enhancements, Parallel Computing, and Error Analysis for BNCT a
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    Chapter 86 Calculation of Absorbed Dose Distributions Using Removal- Diffusion Theory for BNCT Treatment Planning
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    Chapter 87 The Development of a Computational Dosimetry System for BNCT at JAERI
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    Chapter 88 Application of Silicon Diode Arrays for Microdosimetry in BNCT and FNT
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    Chapter 89 Shielding Design and Calculations for the Finnish BNCT Facility
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    Chapter 90 NCT Treatment Room Dose Determinations Using the Monte Carlo Adjoint Shielding (MASH) Method
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    Chapter 91 Radioprotection for Patients and Staff during BNCT at the HFR Petten
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    Chapter 92 Real-Time Absorbed Dose Estimation System for BNCT by PG-SPECT
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    Chapter 93 Utility of Measured Microdosimetric Single Event Spectra in Interpreting Quality of Radiation Fields Used in BNCT
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    Chapter 94 Cell Cluster Models for Microdosimetry
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    Chapter 95 Measurements of Phantom Dose Distributions at the Finnish BNCT Facility
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    Chapter 96 Radioprotection Dosimetry in the European Trial on BNCT Studied by an Anthropomorphic Phantom
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    Chapter 97 Development of a Neutron Energy-Biased in-Air Figure-of-Merit for Predicting in-Phantom BNCT Neutron Beam Characteristics
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    Chapter 98 Reference Phantom Design for the Birmingham BNCT Project
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     Chapter 99 Absorbed Dose Estimates with a High Resolution Voxel-Based Head Phantom
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     Chapter 100 Neutron Capture Therapy (NCT) Enhancement of Fast Neutron Radiotherapy at the University of Washington
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     Chapter 101 Progress towards Boron Neutron Capture Enhancement of Fast Neutron Therapy at the Harper Hospital Neutron Therapy Facility
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     Chapter 102 Characterization of a Modified Fast Neutron Beam for Boron Neutron Capture Enhancement of Fast Neutron Therapy
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     Chapter 103 Modifications to rtt_MC for Fast Neutron Therapy Treatment Planning
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     Chapter 104 Treatment Planning for Boron Neutron Capture Enhanced Fast Neutron Therapy
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     Chapter 105 Modification of the University of Washington Neutron Radiotherapy Facility for Optimization of Neutron-Capture-Enhanced Fast Neutron Therapy
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     Chapter 106 Boron Neutron Capture-Enhanced Fast Neutron Therapy (BNC/FNT) for Non-Small Cell Lung Cancer in Canine Patients
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     Chapter 107 BNCEFN Optimisation with Lead Blocks Collimation and Graphite Embedding
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     Chapter 108 On the Study of a Laminated Beryllium/Tungsten Target for Boron Neutron Capture Enhanced Fast-Neutron Therapy
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     Chapter 109 Progress Toward Fast Neutron Relative Biological Effectiveness Determination Via Proton Bombardment of V79 Cells
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     Chapter 110 A Concise Synthesis of Enantiomerically Pure L -(4-Boronophenyl)Alanine from L -Tyrosine
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     Chapter 111 The Complexation of p -Boronophenylalanine with Alcohols or Carboxylic Acids Studied by Zone Electrophoresis
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     Chapter 112 Recent Developments in the Chemistry of [B 12 H 12 ] 2-
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     Chapter 113 Synthesis of Schiff Bases and Monoalkylamino Derivatives on the Base of Amino- closo -Dodecaborate(1-) Anion [B 12 H 11 NH 3 ] -
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     Chapter 114 Potential BNCT Agents
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     Chapter 115 Borylated Ferrocenium Compounds
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     Chapter 116 Enantioselective Syntheses of 10 B-Enriched L- and D-Carboranylalanine and Their Radiobiological Evaluation in V-79 Chinese Hamster Cells
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     Chapter 117 A Potential New BNCT Agent
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     Chapter 118 Benzoquinone Oxidation of the [ ae -B 20 H 17 NH 3 ] 3- and [ ae -B 20 H 17 OH] 4- Ions
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     Chapter 119 BSMel: An Aromatic Amino Acid Analog of High Boron Content, Easily Prepared from B-10 Enriched and Stereochemically Pure Precursors
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     Chapter 120 Current Status of Selenium Coupling to Hoechst-Carborane
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     Chapter 121 New Synthesis of Boronated Chlorins with Different Lipophilicity
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     Chapter 122 Fluorination of p -Boronophenylalanine
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     Chapter 123 Radioiodination Techniques for Aromatic Amino Acids
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     Chapter 124 Synthetic Approaches to a Novel Iodinated Analogue of BPA
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     Chapter 125 Design of Boron- and Gadolinium-Containing Agents for NCT
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     Chapter 126 On-Line Boron-10 Determination from Blood Samples by ICP-MS
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     Chapter 127 The Role of Dynamic Positron Emission Tomography for Quantifying Boron-10 in Vivo Using the Fructose Complex of Fluorine-18 Labeled Boronophenylalanine
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     Chapter 128 Structure Determination of p -Boronophenylalanine-Fructose Complex Using 1 J cc Coupling Constants
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     Chapter 129 Simultaneous Determination of p -Boronophenylalanine and Boric Acid Using 11 B-NMR
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     Chapter 130 Structure of the BPA-Fructose Complex
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     Chapter 131 Proton MR Spectroscopic Measurement of p -Boronophenylalanine for in Vivo Pharmacokinetic Studies
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     Chapter 132 Subcellular Localization of BSH-Containing and Non-Boron- Containing Chlorin Derivatives in Living Cells Using Confocal Laser Scanning Microscopy
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     Chapter 133 Quantitative Analysis of Boron in Co-Cultures of Human Glioblastoma T98G Cells and Normal Cell Lines within the Same Field of View of Ion Microscopy Imaging
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     Chapter 134 Ion Microscopy Imaging of Boron in Animal Tissue Sections for Neutron Capture Therapy
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     Chapter 135 Ion Microscopy Imaging of Boron from p -Boronophenylalanine in Surgically Acquired Samples of Human Brain Tumor Tissue
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     Chapter 136 In Vitro Exposure of Human T98G Glioblastoma Cells to Mixed BNCT Drugs
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     Chapter 137 A Combination of Immunohistochemistry and Photoelectron Spectromicroscopy for Investigations of Subcellular Boron Distribution
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     Chapter 138 A Method for Determining the Concentration of Boron in Blood by the Measurement of Thermal Neutron Flux Depression
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     Chapter 139 Non-Invasive Quantification of Gadolinium Uptake in Tumors
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     Chapter 140 Subcellular Biodistribution of Na 2 B 12 H 11 SH (BSH) in Rat Glioma Model
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     Chapter 141 Determination of BSH (Na 2 B 12 H 11 SH) Absorbed in Tumor Tissue
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     Chapter 142 Detection of 10 B Distributions in Histological Samples by Neutron Capture Autoradiography Using Cold Neutron Beams and Photoluminescent Imaging Plates
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     Chapter 143 Alpha-Autoradiographic Determination of 10 B Concentrations in Cancer Bearing Mice for Boron Neutron-Capture Therapy
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     Chapter 144 A New Simplified System for the Evaluation of BNCT Pharmaceuticals
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     Chapter 145 Compartmental and Non-Compartmental Methods in Studying the Kinetics of Boron-10 after Boronophenylalanine Fructose Complex (BPA-F)-Infusion in Dogs
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     Chapter 146 Time-Dependent Biodistribution of BPA-F in Normal and Tumor Brain Tissues in Mice
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     Chapter 147 Boron-10 Distribution of p -Boronophenylalanine in the Experimental Brain Tumor in the Rats
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     Chapter 148 BPA Uptake and Efflux through the Cellular Membrane
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     Chapter 149 A Further Mechanism Study of Boron Accumulation to and Release from Melanoma with p -Boronophenylalanine
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     Chapter 150 Enhanced Uptake of Boronophenylalanine and Efficacy of BNCT in F98 Glioma Bearing Rats Following Administration of Cereport™
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     Chapter 151 Effect of Dose and Infusion Time on the Delivery of p - Boronophenylalanine for Neutron Capture Therapy
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     Chapter 152 In Vitro Uptake Study of 5-Carboranyl Uridine and Its Derivatives
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     Chapter 153 Evaluation of Carboranyl 2′-Deoxyuridine Derivatives as Substrates for Human Thymidine Kinases 1 and 2
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     Chapter 154 In Vivo and In Vitro Uptake Study of Boronated Porphyrins for Neutron Capture Therapy
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     Chapter 155 Toxicology of BOPP in Large Animals
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     Chapter 156 Biodistribution Study of Novel Dodecaborate-Phthalocyanines in the B-16 Mouse Melanoma Model
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     Chapter 157 Investigations of the Interaction of Phospholipids with Mercaptoundecahydro- closo -Dodecaborate (2-) (BSH) and Dodecahydro- closo -Dodecaborate (2-) (B 12 H 12 2- )
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     Chapter 158 Membrane Binding of Na 2 B 12 H 11 SH (BSH) with Phosphatidylcholine in Boron Neutron Capture Therapy
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     Chapter 159 Investigation of the Toxicity and Cellular Uptake of Na 4 [B 20 H 17 SH] in EMT6 Cells
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     Chapter 160 Evaluation of the Binding of Polyhedral Borane Compounds to Intracellular Protein Moieties and Monomeric Amino Acids
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     Chapter 161 Cremophor EL Alters Uptake, Retention, Distribution, and Toxicity of the Boron Containing Ether Lipid
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     Chapter 162 Analysis of in Vivo Uptake for Boron Neutron Capture Synovectomy
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     Chapter 163 SLT-Particles for Two-Step Targeting in Boron Neutron Capture Therapy
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     Chapter 164 Application of 10 B Entrapped Liposome to Boron Neutron Capture Therapy for Pancreatic Cancer Model in Vivo
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     Chapter 165 LDL Receptor Status of Human Glioblastoma Cells
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     Chapter 166 The Advantage of Porphyrin for BNCT from the Point of View of Cell Cycle
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     Chapter 167 Strategies to Improve the Efficacy of Neutron Capture Therapy of Brain Tumors by Optimizing Delivery of Boron Compounds
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     Chapter 168 Boron-Rich Oligomeric Phosphate Diesters that Target the Cell Nucleus in Vitro
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     Chapter 169 Biodistribution of Technetium-99m Labeled Epidermal Growth Factor Following Intracarotid Injection into Rats Bearing Intracerebral EGF Receptor (+) Gliomas
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     Chapter 170 Biological Evaluation of Boronated Polyamines as Potential Agents for BNCT
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     Chapter 171 Preclinical Development of β-D-5- o -Carboranyl-2′-Deoxyuridine (D-CDU) for the Treatment of Malignant Brain Tumors
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     Chapter 172 Selective Tumor Uptake of Boronophenylalanine-Fructose (BPA-F) in an Animal Model of Hepatic Colorectal Metastases
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     Chapter 173 BNCT Microdosimetry of a Rat Glioma Model with BPA-F or BSH
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     Chapter 174 Determination of the Compound Factors of BSH and BPA for Glial Progenitor Survival in a Small Animal Model Using Thermal and Epithermal Neutron Irradiation
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     Chapter 175 Analytical Evaluating Method of 10 B(n,αγ) 7 Li Prompt Gamma-Ray Spectrum for Measuring Absorbed Dose Distribution in Boron Neutron Capture Therapy
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     Chapter 176 Modeling the Impact of Near-Threshold 7 Li(p,n) 7 Be Generated, Fast Neutron Beams on Boron Drug Distribution Requirements for BNCT
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     Chapter 177 Computational Dosimetry for Boron Neutron Capture Synovectomy
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     Chapter 178 Application of Thermoluminescent Dosimeters to Mixed Neutron- Gamma Dosimetry for BNCT
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     Chapter 179 Semiconductor Detectors for In-Phantom Thermal Neutron Flux and Boron Dose Measurements in BNCT and Fast Neutron Therapy
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     Chapter 180 Determination of an RBE for an Epithermal Neutron Beam for BNCT from Microdosimetric Measurements
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     Chapter 181 Effects of Neutron Collimation, Beam Size, and Spectrum on In-Phantom Performance of Realistic Epithermal Neutron Beams for BNCT
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     Chapter 182 Dose Distribution in 157 Gd and 10 B Containing Phantoms Subsequent to Irradiation with Thermal Neutrons
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     Chapter 183 252 Cf Mixed-Field Dosimetry for a Variety of Source Geometries and Phantom Materials for Clinical Brachytherapy
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     Chapter 184 157 Gd Photon Dose Enhancement from a Neutron Emitting 252 Cf Point Source
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     Chapter 185 Theoretical Cell Survival Probability for Preclinical Evaluation of BNCT Treatment Conditions
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     Chapter 186 A Monte Carlo Calculation of the Change in Dosimetric Properties on the Usage of Heavy Water for Boron Neutron Capture Therapy
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     Chapter 187 Large Animal Model for Healthy Tissue Tolerance Study in BNCT
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     Chapter 188 A Large Animal Model Study Investigating Potential BNCT Retreatment Using BSH
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     Chapter 189 Dosimetry Chain for the Dogs Irradiated in the Epithermal Neutron Beam at the Finnish BNCT Facility
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     Chapter 190 In Vivo Dosimetry of the Dog Irradiations at the Finnish BNCT Facility
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     Chapter 191 Survival after BNCT in Combination with Surgery for Dogs with Spontaneous Brain Tumors
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     Chapter 192 Quantitative MRI in Assessing Irradiation Effect in Dog Brain
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     Chapter 193 Irradiation of Dog Brain with Single Doses of X-Rays
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     Chapter 194 A Rat Model of Oral Mucosal Response to Boron Neutron Capture Irradiation
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     Chapter 195 Split-Dose BNCT Irradiations of Rat Oral Mucosa and Rat Brain Tumor Using BPA
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     Chapter 196 Efficacy of Boron Neutron-Capture Therapy Using a Carborane- Containing Tetraphenylporphyrin in Mice Bearing EMT-6 Tumors
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     Chapter 197 Apoptosis of Tumor Cells in Response to Boron Neutron Capture Therapy
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     Chapter 198 Apoptosis Induced by Boron Neutron Capture Therapy for Brain Tumors
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     Chapter 199 Cell Cycle Change of 9L Glioma Cell after in Vitro Boron Neutron Capture Therapy
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     Chapter 200 Radiobiological Effects of Boronated Porphyrin (STA-BX909) Compared to BSH in Cultured Glioma Cell Line
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     Chapter 201 Mutagenic Effects at HPRT Locus in Chinese Hamster Ovary (CHO) Cells Induced by Epi-Thermal and Thermal Neutrons
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     Chapter 202 Evaluation of Neurotoxicity and Radiation Effects of BNCT in Rats Following Blood-Brain Barrier Disruption and Intracarotid Injection of BPA or BSH
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     Chapter 203 Cell Survival Following in Vitro Irradiation at Depth in a Lucite Phantom as a Measure of Epithermal Beam RBE
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     Chapter 204 Applicability of Combination with Tirapazamine in Boron Neutron Capture Therapy
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     Chapter 205 Behaviors of Cells in Different Proliferative States within Solid Tumors in Boron and Gadolinium Neutron Capture Therapy When Irradiated with Two Different Cadmium Ratio Neutrons
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     Chapter 206 Depth-Dose Evaluation for Liver Cancer Treatment by BNCT and GDNCT Using an Epithermal Neutron Beam
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     Chapter 207 A Compact Cell Culture Disc for Neutron Capture Radiography
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     Chapter 208 Current Clinical Paradigms in Melanoma BNCT
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     Chapter 209 BNCT Beyond Glioma Treatment
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     Chapter 210 Progress in the Development of Boron Neutron Capture Synovectomy for the Treatment of Rheumatoid Arthritis
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     Chapter 211 Which is the Best Nuclide for NCT?
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     Chapter 212 NCT with Several Agents
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     Chapter 213 Energy Deposited by Electrons in DNA Following n+Gd Interaction
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     Chapter 214 Neutron Capture Therapy (BNCT) and Photodynamic Therapy (PDT) Can Both be Accomplished with a Single Compound
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     Chapter 215 BNCT for the Prevention of Restenosis Following Angioplasty
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     Chapter 216 Operative Modalities and Effects of BNCT on Liver Metastases of Colon Adenocarcinoma