Chapter title |
Aggregate and Heatmap Representations of Genome-Wide Localization Data Using VAP, a Versatile Aggregate Profiler.
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Chapter number | 18 |
Book title |
DNA-Protein Interactions
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Published in |
Methods in molecular biology, January 2015
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DOI | 10.1007/978-1-4939-2877-4_18 |
Pubmed ID | |
Book ISBNs |
978-1-4939-2876-7, 978-1-4939-2877-4
|
Authors |
Brunelle, Mylène, Coulombe, Charles, Poitras, Christian, Robert, Marc-Antoine, Markovits, Alexei Nordell, Robert, François, Jacques, Pierre-Étienne, Mylène Brunelle, Charles Coulombe, Christian Poitras, Marc-Antoine Robert, Alexei Nordell Markovits, François Robert, Pierre-Étienne Jacques |
Abstract |
In the analysis of experimental data corresponding to the signal enrichment of chromatin features such as histone modifications throughout the genome, it is often useful to represent the signal over known regions of interest, such as genes, using aggregate or individual profiles. In the present chapter, we describe and explain the best practices on how to generate such profiles as well as other usages of the versatile aggregate profiler (VAP) tool (Coulombe et al., Nucleic Acids Res 42:W485-W493, 2014), with a particular focus on the new functionalities introduced in version 1.1.0 of VAP. |
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