Chapter title |
Incidence and Clinical Course of Respiratory Viral Coinfections in Children Aged 0–59 Months
|
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Chapter number | 185 |
Book title |
Respiratory Contagion
|
Published in |
Advances in experimental medicine and biology, January 2015
|
DOI | 10.1007/5584_2015_185 |
Pubmed ID | |
Book ISBNs |
978-3-31-930603-2, 978-3-31-930604-9
|
Authors |
A. Nitsch-Osuch, E. Kuchar, A. Topczewska-Cabanek, K. Wardyn, K. Życińska, L. Brydak |
Abstract |
Clinical data available on coinfections are contradictory concerning both the number of viruses involved and the severity of the condition. A total of 114 patients aged 0-59 months with symptoms of respiratory tract infection were enrolled into the study. Nasal and pharyngeal swabs were tested using the PCR method for the following 12 viruses: influenza A, influenza B, respiratory syncytial virus A (RSV A), respiratory syncytial virus B (RSV B), adenovirus, metapneumovirus, coronavirus 229E/NL63 (hCoV229), coronavirus OC43 (hCoVOC43), parainfluenza virus 1 (PIV-1), parainfluenza virus 2 (PIV-2), parainfluenza virus 3 (PIV-3), and rhinovirus A/B. Coinfections were detected in nine (8 %) patients. Five of the coinfections were related to influenza A (H3N2) virus associated with the following other, single or combined, respiratory viruses: influenza B in one case, hCoV229 in two cases, hCoV229, RSV A, and PIV-2 in one case, and PIV-1, PIV-2, RSV A, RSV B, and adenovirus in one case. The other four coinfections were caused by: adenovirus and hCoVOC43, adenovirus, and rhinovirus, RSV A and PIV-1, influenza B, and RSV B. We did not observe any significant differences in the clinical course of infections caused either by a single or multiple viral factors. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 52 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 19% |
Researcher | 6 | 12% |
Student > Ph. D. Student | 6 | 12% |
Student > Postgraduate | 4 | 8% |
Other | 3 | 6% |
Other | 6 | 12% |
Unknown | 17 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 15% |
Medicine and Dentistry | 8 | 15% |
Agricultural and Biological Sciences | 3 | 6% |
Nursing and Health Professions | 3 | 6% |
Veterinary Science and Veterinary Medicine | 2 | 4% |
Other | 7 | 13% |
Unknown | 21 | 40% |