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Title |
Transcriptome analysis of hen preadipocytes treated with an adipogenic cocktail (DMIOA) with or without 20(S)-hydroxylcholesterol
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Published in |
BMC Genomics, February 2015
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DOI | 10.1186/s12864-015-1231-z |
Pubmed ID | |
Authors |
Alemu Regassa, Woo Kyun Kim |
Abstract |
20(S)-hydroxycholesterol (20(S)) potentially reduces adipogenesis in mammalian cells. The role of this oxysterol and molecular mechanisms underlying the adipogenesis of preadipocytes from laying hens have not been investigated. This study was conducted to 1. Analyze genes differentially expressed between preadipocytes treated with an adipogenic cocktail (DMIOA) containing 500 nM dexamethasone, 0.5 mM 3-isobutyl-1-methylxanthine, 20 μg/mL insulin and 300 μM oleic acid (OA) and control cells and 2. Analyze genes differentially expressed between preadipocytes treated with DMIOA and those treated with DMIOA + 20(S) using Affymetrix GeneChip® Chicken Genome Arrays. |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 6% |
Unknown | 16 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 24% |
Student > Master | 4 | 24% |
Professor | 1 | 6% |
Other | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 1 | 6% |
Unknown | 5 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 18% |
Biochemistry, Genetics and Molecular Biology | 2 | 12% |
Medicine and Dentistry | 2 | 12% |
Mathematics | 1 | 6% |
Environmental Science | 1 | 6% |
Other | 2 | 12% |
Unknown | 6 | 35% |