@ARUK_ODDI @BiochemSoc Dang it! Would love to attend this meeting. Intriguing and emerging topic. Suspect DUBs regulate SHIP1/INPP5D and dysregulation if this pathway contributes to severe Crohns Disease. See https://t.co/lKZXszffMG #INPP5D #SHIP1 #IBD
Fantastic work published in @FrontImmunol outlining the role of SHIP-1 loss in #IBD and the importance of how investigating signaling pathways can offer insights into novel therapies https://t.co/KwklZ1hzlN
SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn’s Disease and Peripheral T Cell Reduction: Sandra Fernandes, Neetu Srivastava, Raki Sudan, Frank A. Middleton, Amandeep K. Shergill, James C. Ryan, William G. Kerr https://t.co/
Our new study that shows about 15% of IBD patients don't have suffcient amount of a gene called SHIP1. The SHIP1-deficient patients with Crohn's Disease appear to have more severe disease that requires surgery.#IBD Funded by @CrohnsColitisFn https://t.co/