Title |
Measurement of feline lipase activity using a dry-chemistry assay with a triolein substrate and comparison with pancreas-specific lipase (Spec fPLTM)
|
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Published in |
Journal of Veterinary Medical Science, June 2015
|
DOI | 10.1292/jvms.15-0149 |
Pubmed ID | |
Authors |
Mariko OISHI, OHNO Koichi, SATO Toru, Takashi TAMAMOTO, Hideyuki KANEMOTO, Kenjiro FUKUSHIMA, Hajime TSUJIMOTO |
Abstract |
Pancreatic lipase immunoreactivity (Spec fPL) is currently considered to be the most accurate blood test for the diagnosis of feline pancreatitis. In this study, we measured lipase activity in cats using a newer catalytic lipase assay of dry-chemistry system (FDC-v-LIP) to determine the reference range and compared the results with those for Spec fPL. Based on the results of healthy cats, the reference range of FDC-v-LIP was determined to be less than 30 U/l. FDC-v-lip did not show a strong correlation with Spec fPL in cats with various diseases, which resulted in the low sensitivity and positive predictive value. However, the relatively high (>90%) specificity and negative predictive value indicated that FDC-v-LIP could be a useful patient-side screening test for the exclusion of feline pancreatitis. |
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Unknown | 2 | 100% |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 18 | 100% |
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Readers by professional status | Count | As % |
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Researcher | 5 | 28% |
Professor | 4 | 22% |
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Professor > Associate Professor | 1 | 6% |
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