Title |
Calcium in Kenyon Cell Somata as a Substrate for an Olfactory Sensory Memory in Drosophila
|
---|---|
Published in |
Frontiers in Cellular Neuroscience, May 2018
|
DOI | 10.3389/fncel.2018.00128 |
Pubmed ID | |
Authors |
Alja Lüdke, Georg Raiser, Johannes Nehrkorn, Andreas V. M. Herz, C. Giovanni Galizia, Paul Szyszka |
Abstract |
Animals can form associations between temporally separated stimuli. To do so, the nervous system has to retain a neural representation of the first stimulus until the second stimulus appears. The neural substrate of such sensory stimulus memories is unknown. Here, we search for a sensory odor memory in the insect olfactory system and characterize odorant-evoked Ca2+ activity at three consecutive layers of the olfactory system in Drosophila: in olfactory receptor neurons (ORNs) and projection neurons (PNs) in the antennal lobe, and in Kenyon cells (KCs) in the mushroom body. We show that the post-stimulus responses in ORN axons, PN dendrites, PN somata, and KC dendrites are odor-specific, but they are not predictive of the chemical identity of past olfactory stimuli. However, the post-stimulus responses in KC somata carry information about the identity of previous olfactory stimuli. These findings show that the Ca2+ dynamics in KC somata could encode a sensory memory of odorant identity and thus might serve as a basis for associations between temporally separated stimuli. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
Australia | 1 | 14% |
United Kingdom | 1 | 14% |
Switzerland | 1 | 14% |
Argentina | 1 | 14% |
Unknown | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 4 | 57% |
Members of the public | 3 | 43% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 68 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 21% |
Student > Ph. D. Student | 12 | 18% |
Student > Master | 8 | 12% |
Student > Bachelor | 3 | 4% |
Student > Doctoral Student | 2 | 3% |
Other | 11 | 16% |
Unknown | 18 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 24 | 35% |
Agricultural and Biological Sciences | 13 | 19% |
Biochemistry, Genetics and Molecular Biology | 5 | 7% |
Physics and Astronomy | 4 | 6% |
Psychology | 2 | 3% |
Other | 4 | 6% |
Unknown | 16 | 24% |