The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells #MECFS #LongCovid #myositis https://t.co/FDDmaBwNKy
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https://t.co/H5m1r2LsWW "Furthermore, the helper capacity of cTfh1 cells appears to be restricted to those expressing high levels of ICOS and PD-1."
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https://t.co/H5m1r2LsWW "These cells have different capacity for B cell help; cTfh2 and cTfh17 are capable of helping both naïve and memory B cells produce antibody in vitro;" "while cTfh1 cells provide help to memory B cells, but not naïve cells."
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https://t.co/H5m1r2LsWW "cTfh1 cells express CXCR3, and IFNγ." "Similarly, cTfh17 cells express CCR6 and secrete IL-17." "cTfh2 cells do not express either CXCR3 or CCR6 but can secrete IL-4."