RT @renesugar: https://t.co/y67ZD5hHc7 "Furthermore, inflammation through TLR4 signaling promotes the development of immune suppressive mi…
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https://t.co/y67ZD5hHc7 "Furthermore, inflammation through TLR4 signaling promotes the development of immune suppressive microenvironment, such as recruitment myeloid-derived suppressor cells into local tumor environment, in breast, colon, renal cell, and
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https://t.co/y67ZD5hHc7 "Greten et al. found mouse colitis-associated pro-inflammatory cytokines play a role in colorectal cancer development." "In addition, TLR4-signaling engagement promotes the adhesiveness and metastatic capacity of colorectal cancer
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https://t.co/y67ZD5hHc7 "and promotes downstream beta1 integrin function through the TLR4/MD2 complex, resulting in increased adhesiveness and metastatic capacity of colorectal cancer cells."