Title |
Adipokines, diabetes and atherosclerosis: an inflammatory association
|
---|---|
Published in |
Frontiers in Physiology, November 2015
|
DOI | 10.3389/fphys.2015.00304 |
Pubmed ID | |
Authors |
Leandro C. Freitas Lima, Valdir de Andrade Braga, Maria do Socorro de França Silva, Josiane de Campos Cruz, Sérgio H. Sousa Santos, Matheus M. de Oliveira Monteiro, Camille de Moura Balarini |
Abstract |
Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models. |
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Country | Count | As % |
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Thailand | 1 | 20% |
France | 1 | 20% |
United States | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | <1% |
Poland | 1 | <1% |
Unknown | 226 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 38 | 17% |
Student > Ph. D. Student | 37 | 16% |
Student > Bachelor | 24 | 11% |
Researcher | 19 | 8% |
Student > Doctoral Student | 17 | 7% |
Other | 34 | 15% |
Unknown | 59 | 26% |
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Agricultural and Biological Sciences | 26 | 11% |
Nursing and Health Professions | 14 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 4% |
Other | 28 | 12% |
Unknown | 68 | 30% |