Title |
Coexistence of squamous cell tracheal papilloma and carcinoma treated with chemotherapy and radiotherapy: a case report
|
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Published in |
Therapeutics and Clinical Risk Management, December 2015
|
DOI | 10.2147/tcrm.s95233 |
Pubmed ID | |
Authors |
Dimitrios Paliouras, Apostolos Gogakos, Thomas Rallis, Fotios Chatzinikolaou, Christos Asteriou, Georgios Tagarakis, John Organtzis, Kosmas Tsakiridis, Drosos Tsavlis, Athanasios Zissimopoulos, Ioannis Kioumis, Wolfgang Hohenforst-Schmidt, Konstantinos Zarogoulidis, Paul Zarogoulidis, Nikolaos Barbetakis |
Abstract |
Papillomatosis presents, most frequently, as multiple lesions of the respiratory tract, which are usually considered benign. Malignant degeneration into squamous cell carcinoma is quite common, although curative approaches vary a lot in modern literature. We report a case of a 66-year-old male patient with the coexistence of multiple squamous cell papilloma and carcinoma in the upper trachea with severe airway obstruction that was diagnosed through bronchoscopy and treated by performing an urgent tracheostomy, followed by concurrent chemotherapy and radiotherapy. There was no evidence of recurrence after a 12-month follow-up period. This study underlines the diagnostic and therapeutic value of bronchoscopy as well as multimodality palliative treatment in such cases. To the best of our knowledge, this is the first study to describe an immediate treatment protocol with tracheostomy and concurrent chemotherapy/radiotherapy in a patient with squamous cell tracheal papilloma and carcinoma. |
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