@AlicePopejoy @BarrySlavchic @Nature Martin (2019), highlighting the fact most Genome Wide Association Studies are from Europeans. This may reduce the effectiveness of polygenic risk scores for other populations. Ultimately, it would be ideal to have studi
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@punter05 @raruma @emilynordmann @DrGBuckingham Eg. Martin (2019), the fact most Genome Wide Association Studies are from Europeans is an issue as there are allele frequency differences across populations. This may reduce the effectiveness of polygenic ris
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@thesptrans This has a practical significance as seen in the limitations on biomedical research with most studies featuring Europeans. https://t.co/oT7U3z67YM https://t.co/V8rHSLf7Wh
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RT @Rafal_M: A lot of background reading around population specificity of PRS can be achieved by looking at work from Alicia Martin et al.,…