@angryhacademic Anything that trips the kynurenine pathway can affect mood, attention, etc. Xanthurenic and Kynurenic Acids lab tests https://t.co/8M1Q9bBmH1 Kynurenic (and many other organic acids) https://t.co/yv9xuj7doS https://t.co/V9445Ngl9O
https://t.co/fidtminYs4 "an increase in IDO expression by the iDCs, which depends on the interaction of PD-1 (on MC) with its ligands (PD-L1 and/or PD-L2 on DCs) and which seems to be mediated by an increase in p-STAT-3 in DCs."
Tolerogenic IDO+ Dendritic Cells Are Induced by PD-1-Expressing Mast Cells https://t.co/fidtminYs4
Tolerogenic IDO+ Dendritic Cells Are Induced by PD-1-Expressing Mast Cells https://t.co/eJzApc5Jpu "PD-1 Induces IDO Expression on iDCs Probably via STAT-3 Signaling"