Note of caution: Dynamic regulation and/or prominent expression do not predict function. - miR-21a is dynamically regulated by two promoters and prominently expressed. Nevertheless, it contritubes little to nothing to T-cell development (https://t.co/RmuPo
Whereas some miRNAs, including our favorite miR-181, have a massive impact on development, others are dynamically regulated without apparent function. We want to know why. https://t.co/KRF7nOY8Fs https://t.co/sH8JvtLr0U https://t.co/RmuPoLI1Ca https://t.c
Congrats to Heike! The paper is finally out. So much effort to show that miR-21 does not control T-cell development. Working against publication bias. #miRNA #thymus #immunology. miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development https