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The stacking of adjacent base pairs affect the shape & stability of #DNA. Variants can affect this process: #SNPs with large base pair stacking #FreeEnergy differences led to phenotype variations, & related to #transcriptionfactor binding. #CitedEn
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Trinucleotide Base Pair Stacking Free Energy for Understanding TF-DNA Recognition and the Functions of SNPs. https://t.co/LWlnORpwfF
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Trinucleotide Base Pair Stacking Free Energy for Understanding TF-DNA Recognition and the Functions of SNPs: Gen Li, Yuan Quan, Xiaocong Wang, Rong Liu, Lihua Bie, Jun Gao, Hong-Yu Zhang https://t.co/TDhPTznNcl