The Role of Insulin Resistance and Protein O-GlcNAcylation in Neurodegeneration

RT @renesugar: The Role of Insulin Resistance and Protein O-GlcNAcylation in Neurodegeneration #MECFS #LongCovid https://t.co/0HjCKxvfYe h…

https://t.co/0HjCKxvfYe "and reduction in the production of toxic species of these proteins in preclinical studies."

https://t.co/0HjCKxvfYe "Interestingly, increasing the levels of total O-GlcNAc through highly specific inhibitor of OGA enzyme, Thiamet G has shown promise in the treatment of AD through alleviation of major symptoms of AD through increased O-GlcNAcylati

https://t.co/0HjCKxvfYe "Later studies further confirmed the effect of OGA inhibition on preventing Tau aggregation and amelioration of pathological features in mouse model of tauopathy."